Double immunofluorescence staining for TET2 (Alexafluor 568: red) and

Download scientific diagram | Double immunofluorescence staining for TET2 (Alexafluor 568: red) and SPANX-B or PAGE2 (Alexafluor 488: green) with DAPI counterstaining 20 days post-confluence show overlapping nuclear expression Magnification: 40× (A). More than 95% of cells expressing PAGE2 or SPANX-B were also positive for TET2 staining (B). from publication: Epigenetic Mechanisms Underlying the Dynamic Expression of Cancer-Testis Genes, PAGE2, -2B and SPANX-B, during Mesenchymal-to-Epithelial Transition | Cancer-testis (CT) genes are expressed in various cancers but not in normal tissues other than in cells of the germline. Although DNA demethylation of promoter-proximal CpGs of CT genes is linked to their expression in cancer, the mechanisms leading to demethylation are | Testicular Neoplasms, Myeloma and Computational Thinking | ResearchGate, the professional network for scientists.

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