A new type of nanoparticle can be administered to the lungs, where it can deliver messenger RNA encoding useful proteins. Researchers hope to use them to develop new treatments for cystic fibrosis and other lung diseases.
Novel nanoparticles deliver CRISPR gene editing tools into the cell with much higher efficiency
Lung SORT LNPs enable precise homology-directed repair mediated CRISPR/Cas genome correction in cystic fibrosis models
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Combinatorial design of nanoparticles for pulmonary mRNA delivery and genome editing
MIT scientists develop new nanoparticles to improve vaccine delivery
Combinatorial design of nanoparticles for pulmonary mRNA delivery and genome editing
Inhaled mRNA Therapy Could Be Breath of Fresh Air for Lung Disorders
Nanoparticles can turn off genes in bone marrow cells, MIT News
Scientists harness human protein to deliver molecular medicines to cells, MIT News
Scientists discover a new kind of cell death linked to copper
A Breakthrough in Genome Editing: How NICER Outperforms CRISPR/Cas9
Gene therapy - Wikipedia
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